IL27 Mouse Monoclonal Antibody [Clone ID: B-G49]

CAT#: AM31269PU-N

IL27 mouse monoclonal antibody, clone B-G49, Purified

Conjugation: Unconjugated FITC



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CNY 3,350.00


货期*
5周

规格
    • 2 ml (200 Tests)

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Specifications

Product Data
Clone Name B-G49
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl to label 10e6 cells or 100 µl of whole blood.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human IL-27.
Specificity Recognizes both natural and recombinant Human IL-27
Formulation PBS with 1% BSA as stabilizer and 0.09% Sodium Azide as preservative.
State: Purified
State: Liquid purified IgG fraction.
Purification Ion Exchange Chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Gene Name interleukin 27
Background Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.
Synonyms IL-27 subunit alpha, IL27-A, p28, IL30, IL-30, Interleukin-30
Reference Data
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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