CD4 Mouse Monoclonal Antibody [Clone ID: B-A1]

Specifications

Product Data
Clone Name	B-A1
Applications	FC, FN, IHC
Recommend Dilution	Flow Cytometry. Immunohistochemistry: 1/50. Functional Assay: Inhibits Mixed Lymphocyte Culture.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human thymocytes and jurkat cell lines. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
Specificity	This antibody recognizes a 55 kDa protein.
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free State: Azide Free State: Liquid purfied Ig fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	CD4 molecule
Database Link	Entrez Gene 920 Human UniProt ID P01730
Background	CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45 % of peripheral blood lymphocytes. It is also present on 80 % of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV.
Synonyms	T-cell surface antigen T4/Leu-3
Note	Kd: 0.142 nM
Reference Data
Protein Families	Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways	Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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