IL13 receptor alpha 2 (IL13RA2) Mouse Monoclonal Antibody [Clone ID: B-D13]

Specifications

Product Data
Clone Name	B-D13
Applications	FC, IHC
Recommend Dilution	Flow Cytometry. Immunohistochemistry on Paraffin Embedded Sections. Immunohistochemistry on Frozen Sections and methanol fixed cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	IL-13Ra2 transfected CHO cell line. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
Specificity	Recognizes the soluble antigen. Recognizes the IL-13 receptor a2 (IL-13 Ra2), a 44 kDa protein.
Formulation	Phosphate-buffered saline without carrier and preservatives. This prodcut is sterile-filtered through 0.22 µm and treated to remove endotoxins. State: Azide Free State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	interleukin 13 receptor subunit alpha 2
Database Link	Entrez Gene 3598 Human UniProt ID Q14627
Background	IL-13 receptor alpha 2 belongs to the type I cytokine receptor family; Contains 1 fibronectin type-III domain; Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.
Synonyms	Interleukin-13 receptor alpha-2 chain, IL13RA2, IL-13RA-2, IL13R, IL13 receptor alpha-2, IL-13R-alpha-2
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Jak-STAT signaling pathway

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