CD193 / CCR3 Mouse Monoclonal Antibody [Clone ID: 5E8]

CAT#: AM26800PU-N

CD193 / CCR3 mouse monoclonal antibody, clone 5E8, Purified

Conjugation: Unconjugated APC PE



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CNY 3,140.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 5E8
Applications FC
Recommend Dilution Flow cytometry.
Reactivity Human
Host Mouse
Clonality Monoclonal
Specificity This antibody recognizes CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.
Formulation Phosphate buffered saline (PBS)
State: Purified
State: Liquid Ig fraction
Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration lot specific
Purification Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name C-C motif chemokine receptor 3
Background CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Synonyms C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CKR3, CMKBR3
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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