NR2F6 Mouse Monoclonal Antibody [Clone ID: EM-51]

Specifications

Product Data
Clone Name	EM-51
Applications	WB
Recommend Dilution	Western blot. Positive control: HEK293T/17/NR2F6/Ha-tag transfectants. Negative control: HEK293T/17 cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human NR2F6 protein expressed in E. coli
Specificity	This antibody recognizes NR2F6, a transcriptional repressor expressed mainly in the heart, placenta, liver, skeletal muscle, kidney and pancreas, but also e.g. in T cell subpopulations.
Formulation	Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	nuclear receptor subfamily 2 group F member 6
Database Link	Entrez Gene 2063 Human UniProt ID P10588
Background	NR2F6 (Nuclear receptor subfamily 2 group F member 6), also known as EAR2 or ERBAL2, is a transcription factor involved in modulation of hormonal responses. NR2F6 represses e.g. transcription of the oxytocin-neurophysin gene, renin gene, lutropin-choriogonadotropic hormone receptor gene, and the thyroid hormone receptor gene. In the immune system, NR2F6 affects IL-17 expression in the Th-17 cells, thus also the balance between immunological tolerance and autoimmunity.
Synonyms	EAR2, ERBAL2
Reference Data

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