Bone marrow stromal cell antigen 1 (BST1) Mouse Monoclonal Antibody [Clone ID: SY11B5]

Specifications

Product Data
Clone Name	SY11B5
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow cytometry. Immunoprecipitation. Western blot: non-reducing conditions. Immunohistochemistry (frozen sections).
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CD157
Specificity	This antobody recognizes CD157, an approximately 45 kDa GPI-anchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.
Formulation	Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	bone marrow stromal cell antigen 1
Database Link	Entrez Gene 683 Human UniProt ID Q10588
Background	CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role.
Synonyms	cADPr hydrolase 2, BST-1
Reference Data

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