VCAM1 Mouse Monoclonal Antibody [Clone ID: 1299.27-1]
CAT#: AM26718PU-N
VCAM1 mouse monoclonal antibody, clone 1299.27-1, Purified
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CNY 7,556.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | 1299.27-1 |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on frozen sections: 0.5 μg/ml (1/800). Positive control: Human tonsil. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognizes VCAM-1 (vas cular cell adhesion molecule 1) expressed by endothelial cells in tissue sections and in umbilical vein endothelial cells (HUVECs) stimulated by TNF- α or Interleukin (IL)-1. Maximum expression can be observed after 6 hours as detected by ELISA on these cells. |
Formulation | Phosphate buffered saline pH 7.2 (PBS) State: Purified State: Lyophilized affinity puried Ig fraction Stabilizer: 10mg/ml bovine serum albumin (BSA) Preservative: 0.01% Thimerosal |
Reconstitution Method | Reconstitute by adding 0.5ml distilled water. |
Conjugation | Unconjugated |
Storage Condition | Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Gene Name | vascular cell adhesion molecule 1 |
Database Link | |
Background | VCAM-1 is known to be a receptor for the integrin α 4 β 1, and to interact weakly with the closely related integrin α 4 β 7. The primary leucocytes that interact with CD106 are lymphocytes, monocytes, basophils and eosinophils. Neutrophils lack the α 4 integrin, which explains some of the selective adhesion and recruitment characteristics of the different leucocytes. VCAM-1 is expressed in a wide range of inflammatory conditions, including rejecting cardiac transplant tissue, atherosclerotic lesions, multiple sclerosis, arthritic synovium and inflammatory reactions in the skin. |
Synonyms | V-CAM 1, INCAM-100, L1CAM, VCAM-1 |
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