CD4 Mouse Monoclonal Antibody [Clone ID: EDU-2]

Specifications

Product Data
Clone Name	EDU-2
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on frozen sections: 0.2 μg/ml (1:1000). Has been described to work in FACS. Suggested positive control: Human tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Stimulated human leukocytes
Specificity	This antibody detects CD4.
Formulation	Stock solution contains 0.2 mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative. State: Aff - Purified State: Lyophilized Ig fraction Label: Reconstitute by adding 0.5ml distilled water.
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD4 molecule
Database Link	Entrez Gene 920 Human UniProt ID P01730
Background	CD4 is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is mainly expressed by the T lymphocyte subset that recognizes antigens associated with self MHC class II molecules. CD4 is the primary receptor for HIV retroviruses. Like many cell surface markers, it is a member of the immunoglobulin superfamily.
Synonyms	T-cell surface antigen T4/Leu-3
Note	The antigen is CD4, a 55kD glycoprotein (reduced and nonreduced). The epitope has not been further characterized. Antigen distribution: Isolated cells: the antibody stains approximately 20-60% of human peripheral blood mononuclear cells in flow cytometry.
Reference Data
Protein Families	Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways	Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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