CD37 Mouse Monoclonal Antibody [Clone ID: HH1]

Specifications

Product Data
Clone Name	HH1
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections: 0.5 μg/ml (1/400). Recommended Positive Control: Human tonsil.  Has been described to work in FACS.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This Monoclonal HH1 antibody recognizes the CD37 antigen. Antigen Distribution Isolated cells: The antibody strongly stains approximately 2-10% of human peripheral blood mononuclear cells in flow cytometry. CD37 is present at low density on resting and activated T cells, neutrophils, monocytes and some myelomonocytic leukemia cells. Tissue Sections: The antibody shows a B cell restricted staining pattern.
Formulation	PBS, pH 7.2 State: Aff - Purified State: Lyophilized purified IgG fraction Stabilizer: 5 mg/ml BSA Preservative: 0.09% Sodium Azide
Concentration	0.2 mg/ml (after reconstitution)
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	CD37 molecule
Database Link	Entrez Gene 951 Human UniProt ID P11049
Background	CD37 is strongly expressed on normal and neoplastic mature B lymphocytes. In B-cell ontogeny, the antigen appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. Due to its strong expression, CD37 is a valuable and stable marker for peripheral mature B cells and malignancies thereof. CD37 is extensively glycosylated and typically precipitates as a broad band ranging from 42 to 52kD.
Synonyms	TSPAN26, Tetraspanin-26
Reference Data
Protein Families	Transmembrane
Protein Pathways	Hematopoietic cell lineage

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