T Cell Receptor (TCR) alpha/beta Mouse Monoclonal Antibody [Clone ID: IP26]

Specifications

Product Data
Clone Name	IP26
Applications	FC
Recommend Dilution	Indirect immunofluorescence analysis by Flow cytometry: 1:300.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	The antibody recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 Label: Biotin State: Liquid purified Ig fraction Label: Conjugated with -LC-NHS under optimum conditions. The reagent is free of unconjugated biotin
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2 - 8 °C. DO NOT FREEZE!
Background	The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.
Reference Data

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