smooth muscle Myosin heavy chain 11 (MYH11) (smooth) Mouse Monoclonal Antibody [Clone ID: MS-13]

Specifications

Product Data
Clone Name	MS-13
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 0.25 - 0.5 μg/ml. Immunohistochemistry on frozen and paraffin sections: 0.5 - 1 μg/ml.
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human uterus smooth muscle extract
Specificity	This antibody reacts to Myosin-11 (smooth).
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	myosin, heavy chain 11, smooth muscle
Database Link	Entrez Gene 24582 RatEntrez Gene 4629 Human UniProt ID P35749
Background	Myosin is composed of 2 heavy chains of about 200,000 daltons each and 4 light chains of about 20,000 daltons each. The light chains are of 2 distinct types: the phosphorylatable, regulatory, or MLC2 type, and the nonphosphorylatable, alkali, or MLC1 and MLC3 types (MYL1 according to the HGM symbols). Skeletal Myosin (Fast), also known as MYL1, mapped to the region 2q32.1-qter. Southern blots of a panel of hybrids containing different portions of human chromosome 16 localized the gene to 16p13.13-p13.12. Skeletal Myosin (slow), also known as light chain 3(MYL3), mapped to 3p. Fodor et al. (1989) found that the MYL3 gene has 7 exons, the last of which is completely untranslated 3-prime sequence.
Synonyms	SMMHC, MYH11, KIAA0866, Myosin heavy chain 11, smooth muscle
Reference Data
Protein Pathways	Tight junction, Vascular smooth muscle contraction, Viral myocarditis

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