Aggrecan Mouse Monoclonal Antibody [Clone ID: 4G4/A10]

Specifications

Product Data
Clone Name	4G4/A10
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: Less than 1 µg/ml (Ref.1) Western Blot: 1 µg/ml Immunohistochemistry: 1 µg/ml
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human Aggrecan
Specificity	Monoclonal Ab 4G4/A10 is specific for a core protein epitope of Human articular cartilage. Therefore, in addition to applications in immunochemistry and immunohistochemistry, the 4G4/A10 monoclonal antibody can be used for the detection of aggrecan core protein fragments released during Human inflammatory or degenerative joint diseases into synovial fluid and serum.
Formulation	50 mM TRIS pH 7.4 without preservatives State: Purified State: Lyophilized purifed Cell Culture Supernatant
Reconstitution Method	Restore in aqua bidest to 1 mg/ml.
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	aggrecan
Database Link	Entrez Gene 176 Human UniProt ID P16112
Background	Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains.
Synonyms	ACAN, AGC1, CSPG1, MSK16
Reference Data

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