CD229 (LY9) Mouse Monoclonal Antibody [Clone ID: HLy9.25]

CAT#: AM12140PU-N

CD229 (LY9) mouse monoclonal antibody, clone HLy9.25, Purified



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CNY 3,280.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name HLy9.25
Applications FC, FN, IF, IP, WB
Recommend Dilution Flow cytometry: 6 µg/ml; Use peripheral blood lymphocytes as positive control.
Immunoprecipitation.
Western blot.
Immunocytochemistry.
Functional Application (regulation of activation).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen CD299-transfected 300.19 pre-B cell line
Specificity The antibody recognizes CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name lymphocyte antigen 9
Background CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
Synonyms Ly-9
Reference Data
Protein Families Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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