ENPP3 Mouse Monoclonal Antibody [Clone ID: NP4D6]

CAT#: AM12003PE-N

ENPP3 mouse monoclonal antibody, clone NP4D6, PE

Conjugation: Unconjugated APC FITC PE



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CNY 4,340.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name NP4D6
Applications FC, IF
Recommend Dilution Flow Cytometry analysis of Human blood cells using 20 µl reagent/100 ml of whole blood or 10e6 cells in a suspension.
The content of a vial (2 ml) is sufficient for 100 tests.
Immunofluorescence.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen HEK-293 cells transfected with Human CD203c
Specificity The antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
Formulation PBS
Label: PE
State: Liquid purified Ig fraction
Stabilizer: 0.2% high-grade protease free BSA as a stabilizing agent
Preservative: 15 mM Sodium Azide
Label: Conjugated with R-Phycoerythrin under optimum conditions
Purification Size-Exclusion Chromatography
Conjugation PE
Storage Condition Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!.
This antibody is photosensitive and should be protected from light.
Gene Name ectonucleotide pyrophosphatase/phosphodiesterase 3
Background CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.
Synonyms E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Metabolic pathways, Nicotinate and nicotinamide metabolism, Pantothenate and CoA biosynthesis, Purine metabolism, Riboflavin metabolism, Starch and sucrose metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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