CD162 (SELPLG) Mouse Monoclonal Antibody [Clone ID: TC2]

CAT#: AM12002PU-N

CD162 (SELPLG) mouse monoclonal antibody, clone TC2, Aff - Purified

Conjugation: Unconjugated APC FITC PE



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CNY 3,280.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name TC2
Applications FC, IHC
Recommend Dilution Flow Cytometry: 1.5-2.5 µg/ml.
Positive Control: Human peripheral blood.
This clone has been described to work in Immunohistochemistry on Paraffin Sections.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human thymocytes.
Specificity The antibody TC2 reacts with CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes; it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
Formulation PBS, pH~7.4
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pur by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name selectin P ligand
Background CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.
Synonyms PSGL-1, Selectin P ligand, SELPLG
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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