CD175s Mouse Monoclonal Antibody [Clone ID: STN219]

Specifications

Product Data
Clone Name	STN219
Applications	FC, IF, IHC
Recommend Dilution	Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears) For IHC dilute concentared antibody at 1/50-1/100, use streptavidin~biotin system or polymer system, incubate 30 minutes at room temperature. Immunofluorescence. Flow Cytometry. Recommended Positive Control: Human gastrointestinal tumor, prostate, ovary ca
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Ovine submaxillary mucin (OSM)
Specificity	The specificity of this antibody is similar to B 72.3 antibody. Cellular Localization: Cytoplasmic, apical membrane, luminal.
Formulation	PBS, pH 7.4 containing 1% BSA as stabilizer and 0.05% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Sialosyl Tn antigen also known as CD175s is expressed in the majority of colon, gastric, breast and lung carcinoma. The sialosyl Tn has limited expression to being absent in normal colon, pancreas, stomach, ovary, and prostate. This antigen is detected in several adenocarcinomas. It appears to be useful marker for poorly differentiated colon adenocarcinomas. This antibody stains colon carcinomas and ovarian mucinous carcinomas producing apical cytoplasmic, apical membrane or luminal staining patterns. It is negative with majority of adult tissue sections.
Synonyms	Sialosyl Tn, Sialosyl-Tn, Sialyl Tn, sTn
Reference Data

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