MASPIN (SERPINB5) Mouse Monoclonal Antibody [Clone ID: AT2N6]

Specifications

Product Data
Clone Name	AT2N6
Applications	ELISA, IF, WB
Recommend Dilution	ELISA. Immunofluorescence. Western blot (1:1,000 - 1:2,000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Maspin (1-375 aa) purified from E. coli
Specificity	The antibody recognizes human Serpin B5 (Maspin). Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	serpin family B member 5
Database Link	Entrez Gene 5268 Human UniProt ID P36952
Background	Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas.
Synonyms	Serpin B5, PI5, PI-5
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	p53 signaling pathway

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