TSH beta (TSHB) Mouse Monoclonal Antibody [Clone ID: TSH-2]

Specifications

Product Data
Clone Name	TSH-2
Applications	ELISA
Recommend Dilution	ELISA: This antibody when conjugated with HRP Cat.-No AM32631HR-N can be used as Tracer in Sandwich ELISA for Human TSH detection in combination with anti-TSH Antibody Cat.-No AM09311PU-N (Mouse anti Human TSH monoclonal antibody, Clone TSH-1).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human TSH
Specificity	This antibody is reactive to beta chain of Human TSH.
Formulation	0.01M PBS, pH 7.2 without preservatives State: Aff - Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Concentration	1.0 mg/ml (after reconstitution)
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	thyroid stimulating hormone beta
Database Link	Entrez Gene 7252 Human UniProt ID P01222
Background	Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. TSH has a alpha subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.
Synonyms	Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta
Reference Data

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