TSH beta (TSHB) Mouse Monoclonal Antibody [Clone ID: TSH-2]

Specifications

Product Data
Clone Name	TSH-2
Applications	ELISA
Recommend Dilution	ELISA: This antibody can be used as Tracer in Sandwich ELISA with our matched anti-TSH Antibody Cat.-No AM09311PU-N (Mouse anti Human TSH monoclonal antibody, Clone TSH-1). The suggested tracer concentration is 1/1000 dilution.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human TSH
Specificity	This antibody is reactive to beta chain of Human TSH
Formulation	50% 0.01M PBS, pH 7.2 and 50% Glycerol Label: HRP State: Liquid purified IgG fraction
Purification	Affinity Chromatography on Protein G
Conjugation	HRP
Storage Condition	Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	thyroid stimulating hormone beta
Database Link	Entrez Gene 7252 Human UniProt ID P01222
Background	Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
Synonyms	Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta
Reference Data

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