Hepatitis B Surface Antigen / HBsAg Mouse Monoclonal Antibody [Clone ID: RM-1]

Specifications

Product Data
Clone Name	RM-1
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	Reactive with Hepatitis B Surface Antigen (HBsAg).
Formulation	0.01M PBS, pH 7.0 without preservatives. State: Aff - Purified State: Lyophilized purified Ig fraction.
Reconstitution Method	Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml
Purification	Affinity chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Background	Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Synonyms	HBV surface antigen, Hepatitis B Virus
Reference Data

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