FUS2 (NAT6) Mouse Monoclonal Antibody [Clone ID: AT2F4]

Specifications

Product Data
Clone Name	AT2F4
Applications	ELISA, IF, WB
Recommend Dilution	ELISA. Western blot (1:500 - 1:1,000). Immunofluorescence (1:500 - 1:1,000).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant FUS2 (1-308 aa) purified from E. coli
Specificity	The antibody recognizes human and mouse (Western blot) NAT6 (FUS2). Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	N-acetyltransferase 6
Database Link	Entrez Gene 24142 Human UniProt ID Q93015
Background	Vertebrate FUS2 genes, which are known to be putative tumor suppressor gene, contain several important domains such as the catalytic N-acetyltransferase (NAT) domain. NAT domain is essential enzymes involved in several sophisticated cellular processes such as N-acetylation, O-acetylatin. NAT enzymes may be involved in susceptibility to cancer including colorectal cancer because of the presence of carcinogenic heterocyclic amines in some cooked foods. FUS2 was physically localized to the cytoplasm. Also, FUS2 showed the actin dependent movement, closely related to the polarization in the budding yeast, Saccharomyces cerevisiae.
Synonyms	N-acetyltransferase 6, FUS-, Protein fusion-2
Reference Data
Protein Pathways	Glycerophospholipid metabolism, Limonene and pinene degradation, Phenylalanine metabolism, Tyrosine metabolism

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