TMEM16A (ANO1) Mouse Monoclonal Antibody [Clone ID: DOG1.1]
CAT#: AM09094SU-S
TMEM16A (ANO1) mouse monoclonal antibody, clone DOG1.1, Supernatant
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CNY 4,928.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | DOG1.1 |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: Use at 1/50-1/100 dilution when using a polymer detection system such as UnoVue or PolyVue systems. Paraffin-embedded tissue sections require high temperature antigen unmasking using 10 mM Citrate buffer, pH 6.0 prior to Immunostaining. Suggested Incubation Time: 30-60 minutes at room temperature. Positive Control: Gastrointestinal stromal tumor tissue. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of Human DOG1 protein. |
Specificity | DOG1 is expressed ubiquitously in gastrointestinal stromal tumors irrespective of c-kit or PDGFR alpha mutation status. Reactivity for DOG1 may aid in the diagnosis of gastrointestinal stromal tumors, including PDGFRA mutants that fail to express c-kit antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the c-kit tyrosine kinase. Cellular Localization: Cytoplasmic and membrane. |
Formulation | Buffer, pH 7.5, containing BSA and Sodium Azide as preservatives. State: Supernatant State: Liquid Tissue Culture Supernatant |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. DO NOT FREEZE! |
Gene Name | anoctamin 1 |
Database Link | |
Background | DOG1 gene, a gastrointestinal stromal tumor (GIST) specific gene, encoding for the hypothetical protein FLJ10261, which was named Discovered on GIST 1 (DOG1). DOG1 protein is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFR alpha mutation status. |
Synonyms | Anoctamin-1, Transmembrane protein 16A, DOG-1, ORAOV2, TAOS2, TMEM16A |
Reference Data | |
Protein Families | Transmembrane |
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