STEAP1 Mouse Monoclonal Antibody [Clone ID: J2D2]

Specifications

Product Data
Clone Name	J2D2
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/1000-1/2000. Immunofluorescence: 1/100-1/300. Immunohistochemsitry on Praffin Sections: 1/50-1/100.
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human STEAP1 (1-70 aa) purified from E. coli
Specificity	The antibody recognizes STEAP1.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	six transmembrane epithelial antigen of the prostate 1
Database Link	Entrez Gene 26872 Human UniProt ID Q9UHE8
Background	Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. NCBI Accession No: NP_036581
Synonyms	STEAP-1, Metalloreductase STEAP1, PRSS24
Reference Data

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