HSP27 (HSPB1) Mouse Monoclonal Antibody [Clone ID: 2A5]

CAT#: AM09016PU-S

HSP27 (HSPB1) mouse monoclonal antibody, clone 2A5, Purified

Size: 50 ul 100 ul



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CNY 5,630.00


货期*
5周

规格
    • 50 ul

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Specifications

Product Data
Clone Name 2A5
Applications ELISA, IHC, WB
Recommend Dilution ELISA.
Western blot (1:1,000 - 1:2,000).
Immunohistochemistry on Parffin embedded tissue (1:50).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant human Hsp27 (1-205 aa) purified from E. coli
Specificity The antibody recognizes human Hsp27.
Other species not tested.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-G affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name heat shock protein family B (small) member 1
Background Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.
Synonyms Heat shock protein beta-1, Heat shock 27 kDa protein, HSP28, 28 kDa heat shock protein, SRP27, HSP25
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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