CDK2 Mouse Monoclonal Antibody [Clone ID: 4i33]

Specifications

Product Data
Clone Name	4i33
Applications	ELISA, IHC, IP, WB
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Immunoprecipitation. Western Blot.
Reactivity	Human, Mouse, Xenopus
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human CDK2
Specificity	Recognizes Human CDK2 (MW 33kD). Does not cross-react with other CDKs.
Formulation	0.1M Tris-glycine, pH 7.4, 150mM Sodium Chloride State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cyclin-dependent kinase 2
Database Link	Entrez Gene 1017 Human UniProt ID P24941
Background	Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.
Synonyms	p33 protein kinase
Reference Data

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