Influenza A (Nucleoprotein) Mouse Monoclonal Antibody [Clone ID: FluA-NP 4F1]

Specifications

Product Data
Clone Name	FluA-NP 4F1
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot: 1-5 µg/ml. Immunostaining: 1-5 µg/ml.
Reactivity	Influenza A Virus
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Influenza virus type A Nucleoprotein (NP).
Specificity	This antibody has been shown to specifically recognize type A influenza virus NP in virus infected cell culture and patients' samples.
Formulation	100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56 (Portela et al 2002).
Synonyms	Influenza A Virus, Seasonal Flu
Note	To insure lot-to-lot consistency, each batch of product is tested by ELISA and/or Western Blot to conform to the characteristics of a standard reference reagent.
Reference Data

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