CD79B Mouse Monoclonal Antibody [Clone ID: CB3-1]

Specifications

Product Data
Clone Name	CB3-1
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry: ? 1 µg/106 cells. Immunohistochemistry on Frozen Sections (Reported). Immunoprecipitation (Reported in Ref 1,2).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Ramos B cells.
Specificity	This antibody reacts with the beta chain of CD79. (Ref.1-4)
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD79b molecule
Database Link	Entrez Gene 974 Human UniProt ID P40259
Background	CD79 is a 23/21 disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29). CD79b is the B cell antigen receptor Ig beta chain (BCR Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer tranduces signals. CD79 beta is a B cell specific marker, valuable for the detection of B cells at all maturation stages.
Synonyms	B29, IGB, B-Cell marker
Reference Data

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