Chicken Macrophages (+ Monocytes) Mouse Monoclonal Antibody [Clone ID: KUL01]

Specifications

Product Data
Clone Name	KUL01
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,2) Immunohistochemistry. (Ref.1)
Reactivity	Chicken
Host	Mouse
Clonality	Monoclonal
Immunogen	Chicken perpheral blood mononuclear cell leukocytes
Specificity	This antibody is specific to Chicken Monocytes and Macrophages. The antibody does not react with B (Bu-1+) or T (CD3+) lymphocytes. This antibody is useful in the study of the development, distribution, function and ontogeny of the mononuclear phagocyte system (MPS) of the chicken by exclusively recognizing the cells of the MPS. It identifies Chicken Monocytes and Macrophages as well as interdigitating cells and activated microglia cells.
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Monocyte and macrophage are white blood cells that roam the body tissues engulfing foreign organisms. A monocyte is a leukocyte, part of the human body's immune system that protects against blood-borne pathogens and moves quickly (aprox. 8-12 hours) to sites of infection in the tissues. Monocytes are usually identified in stained smears by their large bi-lobed nucleus. Macrophages are cells within the tissues that originate from specific white blood cells called monocytes. Monocytes and macrophages are phagocytes, acting in both nonspecific defense (or innate immunity) as well as specific defense (or cell-mediated immunity) of vertebrate animals. Their role is to phagocytize (engulf and then digest) cellular debris and pathogens either as stationary or mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen.
Reference Data

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