Chicken Lambda light chain Mouse Monoclonal Antibody [Clone ID: L-1]
CAT#: AM08129PU-N
Chicken Lambda light chain mouse monoclonal antibody, clone L-1, Purified
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CNY 4,862.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | L-1 |
Applications | ELISA, FC, IF, IHC |
Recommend Dilution | ELISA. Flow Cytometry. Immunofluorescence. Immunohistochemistry on Frozen Sections. |
Reactivity | Chicken |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognizes Lambda light chains of Chicken Immunoglobulin. (Ref.1) |
Formulation | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Background | All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins). |
Synonyms | Ig lambda chain C regions |
Reference Data |
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