CD8B Mouse Monoclonal Antibody [Clone ID: EP42]

Specifications

Product Data
Clone Name	EP42
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry. (Ref.2) Immunoprecipitation. (Ref.2) Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections. (Ref.4)
Reactivity	Chicken
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes beta chain of Chicken CD8 (Mr. 34 kDa).
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD8b molecule
Database Link	Entrez Gene 396175 Chicken UniProt ID Q90769
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow. (Ref.1,2)
Synonyms	CD8B, CD8B1
Reference Data

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