CD4 Mouse Monoclonal Antibody [Clone ID: EP96]

Specifications

Product Data
Clone Name	EP96
Applications	FC, FN, IHC, IP
Recommend Dilution	Flow Cytometry. (Ref.1) Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections): Identification and localization of CD4+ T cells Immunoprecipitation. (Ref.1,2) Inhibition of mitogen-induced proliferation (Ref.1,2)
Reactivity	Chicken
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes Chjicken CD4 (Mr. 64 kDa). EP96 inhibits both PHA- and Con A-induced proliferative responses of splenocytes, and PWM-induced IL-2 production. (Ref.1)
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID Q6Q4G0
Background	CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
Synonyms	T-cell surface antigen T4/Leu-3
Reference Data

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