H2-D1 Mouse Monoclonal Antibody [Clone ID: 27-11-13S]
CAT#: AM08082FC-N
H2-D1 mouse monoclonal antibody, clone 27-11-13S, FITC
Conjugation: Unconjugated Biotin PE
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CNY 5,071.00
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Specifications
Product Data | |
Clone Name | 27-11-13S |
Applications | FC |
Recommend Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-3) |
Reactivity | Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | C3H alphaBDF1 splenocytes. (Ref.1) |
Specificity | This antibody recognizes the alpha 3 domain of H-2Db class I MHC antigen. It cross-reacts with the alpha 3 domain of H-2Ld, H-2Dq and H-2Lq, but not H-2Kd or H-2Dd. Reactivity with haplotypes k, f, p, r, and s has not been observed. Customer feedback: Clone 27-11-13S does not cross-react with human cells. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | lot specific |
Conjugation | FITC |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
Gene Name | histocompatibility 2, D region locus 1 |
Database Link | |
Background | In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant beta 2 Microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells. |
Synonyms | H-2D(B), H2-D1 |
Reference Data |
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