CD45 / LCA (CD45RC) Rat Monoclonal Antibody [Clone ID: C455.1F]
CAT#: AM08070PU-N
CD45 / LCA (CD45RC) rat monoclonal antibody, clone C455.1F, Purified
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CNY 5,071.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | C455.1F |
Applications | FC, IP |
Recommend Dilution | Flow Cytometry: Identification and enumeration of CD45RC+ cells. Immunoprecipitation. |
Reactivity | Mouse |
Host | Rat |
Clonality | Monoclonal |
Specificity | This antibody recognises an exon C-dependent epitope of CD45 glycoprotein. |
Formulation | 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | protein tyrosine phosphatase, receptor type, C |
Database Link | |
Background | The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. (Ref.1-4) The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species (See also products AM08044). (Ref.1-4)The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform. |
Synonyms | PTPRC, Leukocyte common antigen, L-CA, T200 |
Reference Data |
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