Tfrc Rat Monoclonal Antibody [Clone ID: RI7217]

CAT#: AM08050PU-N

Tfrc rat monoclonal antibody, clone RI7217, Purified

Conjugation: Unconjugated Biotin FITC PE



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CNY 4,092.00


货期*
4周

规格
    • 500 ug

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Specifications

Product Data
Clone Name RI7217
Applications FC, FN, IP
Recommend Dilution Flow Cytometry. (Ref.1-3,5)
In vivo and vitro Inhibition of Cell Proliferation. (Ref.2)
Immunoprecipitation. (Ref.3)
Reactivity Mouse
Host Rat
Clonality Monoclonal
Specificity This antibody recognises CD71/Transferrin Receptor, Mr 180-190 kDa (90-95 kDa under reducing conditions).
RI7217 inhibits cell proliferation in vitro. (Ref.2)
Formulation 100 mM Borate Buffered Saline, pH 8.2.
No preservatives or amine-containing buffer salts added.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name transferrin receptor
Background CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the Transferrin Receptor. It is essential for the growth of normal and neoplastic cells. (Ref.1,4) It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. (Ref.4) Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major ironcarrying protein. It may also be involved in signal transduction via its association with the T cell receptor zeta chain.
Synonyms TfR1, p90, Transferrin receptor protein 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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