Cd2 Rat Monoclonal Antibody [Clone ID: 12-15]

Specifications

Product Data
Clone Name	12-15
Applications	FC, FN, IP
Recommend Dilution	Flow Cytometry < / = 1 µg/10e6 cells. (Ref.1-3) Immunoprecipitation. (Ref.1-2) Functional Assay: In vitro Inhibition of CTL-mediated lysis. (Ref.1) Induction of T cell unresponsiveness in vivo. (Ref.4)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody is specific to CD2/LFA-2 (Mr 45-58 kDa)
Formulation	PBS without preservatives. State: Low Endotoxin State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	CD2 antigen
Database Link	Entrez Gene 12481 Mouse UniProt ID P08920
Background	CD2, also known as leukocyte function-associated antigen-2 (LFA-2), is a member of the immunoglobulin superfamily of cell adhesion molecules. (Ref.1) It is expressed on the surface of >95% of thymocytes, and essentially all B cells, T cells and NK cells. (Ref.1-3) In the mouse, CD2 is the receptor for CD48. (Ref.4) CD2 is thought to play a major role in mediating T-cell adhesion, T-cell recognition/activation, T-cell signaling and intrathymic differentiation. (Ref.5-10)
Synonyms	SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor
Reference Data

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