HSP90AA1 Mouse Monoclonal Antibody [Clone ID: 5G5]

Specifications

Product Data
Clone Name	5G5
Applications	ELISA, FC, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400.  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human HSP90AA1 expressed in E. Coli.
Specificity	Recognizes HSP90AA1 / HSP90 alpha
Formulation	PBS State: Purified State: Liquid purified antibody Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	90 kDa
Gene Name	heat shock protein 90kDa alpha family class A member 1
Database Link	Entrez Gene 3320 Human UniProt ID P07900
Background	HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
Synonyms	HSP90A, HSPC1, HSPCA, Heat shock 86 kDa, HSP86, NY-REN-38, Heat shock protein HSP 90-alpha
Reference Data

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