GSTM1 Mouse Monoclonal Antibody [Clone ID: 1H4A4]

CAT#: AM06705SU-N

GSTM1 mouse monoclonal antibody, clone 1H4A4, Ascites



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CNY 5,775.00


货期*
5周

规格
    • 100 ul

Specifications

Product Data
Clone Name 1H4A4
Applications ELISA, FC, IHC, WB
Recommend Dilution Western Blot: 1/500 - 1/2000.
Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: 1/10000.
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of human GSTM1 expressed in E. Coli.
Specificity This antibody reacts to GSTM1.
Formulation State: Ascites
State: Ascitic fluid containing 0.03% sodium azide.
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Predicted Protein Size 26 kDa
Gene Name glutathione S-transferase mu 1
Background Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Synonyms Glutathione S-transferase Mu 1, GST class-mu 1, GSTM1-1, GST1, GSTM1a-1a, GSTM1b-1b, GTH4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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