alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: 4F4]

Specifications

Product Data
Clone Name	4F4
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human ACTA2 expressed in E. Coli.
Specificity	Recognizes ACTA2
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	42 kDa
Gene Name	actin, alpha 2, smooth muscle, aorta
Database Link	Entrez Gene 59 Human UniProt ID P62736
Background	The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms	ACTSA, ACTVS, Alpha-actin-2
Reference Data

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