GFI1 Mouse Monoclonal Antibody [Clone ID: 5D7]
CAT#: AM06509SU-N
GFI1 mouse monoclonal antibody, clone 5D7, Ascites
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CNY 5,346.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 5D7 |
Applications | ELISA, WB |
Recommend Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human GFI1 expressed in E. Coli. |
Specificity | Recognizes GFI1 |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | 45 kDa |
Gene Name | growth factor independent 1 transcriptional repressor |
Database Link | |
Background | This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Expression of GFl1 ranges from the hematopoietic and lymphoid system, to sensory epithelia, lung and parts of the CNS. |
Synonyms | Zinc finger protein 163, GFI1, Gfi-1 |
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