IKB beta (NFKBIB) Mouse Monoclonal Antibody [Clone ID: 7B4]

Specifications

Product Data
Clone Name	7B4
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human NFKBIB expressed in E. Coli.
Specificity	Recognizes NFKBIB / IKBB
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	45 kDa
Gene Name	NFKB inhibitor beta
Database Link	Entrez Gene 4793 Human UniProt ID Q15653
Background	Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.
Synonyms	I-kappa-B-beta, TRIP9, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9
Reference Data

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