alpha 1 Antitrypsin (SERPINA1) Mouse Monoclonal Antibody [Clone ID: 2B12]

Specifications

Product Data
Clone Name	2B12
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human AAT expressed in E. Coli.
Specificity	Recognizes AAT, also known as SERPINA1
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	47 kDa
Gene Name	serpin family A member 1
Database Link	Entrez Gene 5265 Human UniProt ID P01009
Background	AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
Synonyms	SERPINA1, AAT
Reference Data

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