Eph receptor B4 (EPHB4) Mouse Monoclonal Antibody [Clone ID: 5B5]

Specifications

Product Data
Clone Name	5B5
Applications	IF, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.
Specificity	Recognizes EPH receptor B4 (EphB4).
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	108 kDa
Gene Name	EPH receptor B4
Database Link	Entrez Gene 2050 Human UniProt ID P54760
Background	EPH receptor B4 (EphB4), also known as Htk, Myk1, Tyro11 is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.
Synonyms	Ephrin type-B receptor 4, HTK, TYRO11
Reference Data

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