SOX2 Mouse Monoclonal Antibody [Clone ID: 10F10C9]

Specifications

Product Data
Clone Name	10F10C9
Applications	WB
Recommend Dilution	ELISA: 1/10000. Western Bloting: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.
Specificity	Recognizes SRY (sex determining region Y)-box 2 (SOX2).
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	SRY-box 2
Database Link	Entrez Gene 6657 Human UniProt ID P48431
Background	This protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Synonyms	Transcription factor SOX-2, ANOP3, MCOPS3, SRY-box 2
Reference Data

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