FRK Mouse Monoclonal Antibody [Clone ID: 1A8H2C12]
CAT#: AM06251SU-N
FRK mouse monoclonal antibody, clone 1A8H2C12, Ascites
Need it in bulk or conjugated?
Get a free quote
CNY 4,536.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 1A8H2C12 |
Applications | ELISA, IHC, WB |
Recommend Dilution | ELISA: 1/10000. Western blot: 1/500-1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of FRK (aa2-300) expressed in E. Coli. |
Specificity | Recognizes FRK. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | fyn related Src family tyrosine kinase |
Database Link | |
Background | Src is the human homolog of the v-src gene of the Rous sarcoma virus, also known as avian sarcoma virus or ASV. Src is the first proto-oncogenic nonreceptor tyrosine kinase characterized in human. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility, and adhesion. Src-family kinases contain an amino terminal cell membrane anchor followed by an SH3 domain and an SH2 domain involved in modular association and activation, respectively. Frk (Rak) is an epithelial tissue-specific kinase. The human Rak gene maps to chromosome 6q21-q22.3 and encodes a 505 amino acid protein. The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. |
Synonyms | RAK, FYN-related kinase |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Customer
Reviews
Loading...