Eph receptor A1 (EPHA1) Mouse Monoclonal Antibody [Clone ID: 5D2]

Specifications

Product Data
Clone Name	5D2
Applications	ELISA, IHC, WB
Recommend Dilution	Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of EphA1 expressed in E. Coli.
Specificity	This antibody recognizes Human EphA1. Other species not tested.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	108 kDa
Gene Name	EPH receptor A1
Database Link	Entrez Gene 2041 Human UniProt ID P21709
Background	EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.
Synonyms	Ephrin type-A receptor 1, EPH, EPHT, EPHT1
Reference Data

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