K8 (K8 alpha) Mouse Monoclonal Antibody [Clone ID: 8C12G10G1]

Specifications

Product Data
Clone Name	8C12G10G1
Applications	IF, WB
Recommend Dilution	ELISA: 1/10000.  Western Blot: 1/500 - 1/2000.  Immunofluorescence: 1/200 - 1/1000.  Immunohistochemistry: 1/200 - 1/1000.
Reactivity	Kaposi-Sarkom-Herpesvirus
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of KSHV K8α expressed in E. Coli.
Specificity	This antibody recognizes KSHV K8 alpha
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID Q2HR82
Background	Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV K8 and K8.1 open reading frames are juxtaposed and span from nucleotide (nt) 74850 to 76695 of the virus genome. A K8 pre-mRNA overlaps the entire K8.1 coding region, and alternative splicing of KSHV K8 and K8.1 pre-mRNAs each produces three isoforms (α, β, and γ) of the mRNAs.
Synonyms	KSHV K8, Human gammaherpesvirus 8, HHV-8
Reference Data

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