Vcam1 Rat Monoclonal Antibody [Clone ID: MVCAM A (429)]

Specifications

Product Data
Clone Name	MVCAM A (429)
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/10-1/50 diluted antibody to label 106 cells in 100 µl.   Immunohistochemistry on Frozen Sections.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Stromal cell line PA6
Specificity	This antibody recognizes vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. Clone MVCAM A (429) is reported to partially block VCAM-1 mediated functions (See Kinashi, T. and  Springer, T.A. for details).
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	vascular cell adhesion molecule 1
Database Link	Entrez Gene 22329 Mouse UniProt ID P29533
Background	CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29).
Synonyms	V-CAM 1, INCAM-100, L1CAM, VCAM-1
Reference Data

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