Rb (RB1) Mouse Monoclonal Antibody [Clone ID: XZ133]

CAT#: AM05255PU-N

Rb (RB1) mouse monoclonal antibody, clone XZ133, Purified



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CNY 5,937.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name XZ133
Applications IP
Recommend Dilution Immunoprecipitation.
Reactivity Chicken, Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Recombinant protein corresponding to amino acids 387 to 982 of the human retinoblastoma sequence.
Specificity Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors.
Formulation PBS containing 0.08% Sodium Azide as preservative.
State: Purified
State: Liquid (sterile filtered) purified IgG fraction.
Concentration lot specific
Purification From ascites.
Conjugation Unconjugated
Storage Condition Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Gene Name RB transcriptional corepressor 1
Background Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.
Synonyms Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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