PAI1 (SERPINE1) Mouse Monoclonal Antibody [Clone ID: 3E529]
CAT#: AM05029PU-N
PAI1 (SERPINE1) mouse monoclonal antibody, clone 3E529, Purified
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CNY 8,547.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | 3E529 |
Applications | ELISA |
Recommend Dilution | ELISA. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant human PAI |
Specificity | This antibody recognizes both free and complexed forms of Human PAI-1. |
Formulation | 0.05M Sodium phosphate, 0.1M Sodium chloride, 1mM EDTA, pH 6.6 State: Purified State: Liquid purified Ig |
Concentration | lot specific |
Purification | >98% pure (SDS-PAGE). Protein A chromatography |
Conjugation | Unconjugated |
Storage Condition | Upon receipt, store undiluted (in aliquots) at -20°C or long term (in aliquots) at -70°C. Avoid repeated freezing and thawing. |
Gene Name | serpin family E member 1 |
Database Link | |
Background | PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder. |
Synonyms | Serpin E1, PLANH1, Plasminogen Activator Inhibitor 1, PAI-1, PAI |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Complement and coagulation cascades, p53 signaling pathway |
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