PPP1R14A Mouse Monoclonal Antibody [Clone ID: 4H10]

Specifications

Product Data
Clone Name	4H10
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot: 1:250 ~ 1:1000 (1:500 as startin dilution).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PPP1R14A (1-147aa) purified from E. coli
Specificity	This antibody detects PPP1R14A.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	protein phosphatase 1 regulatory inhibitor subunit 14A
Database Link	Entrez Gene 94274 Human UniProt ID Q96A00
Background	PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization.
Synonyms	Protein phosphatase 1 regulatory subunit 14A, CPI-17, CPI17, PPP1INL
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.